Synthesis, biological evaluations and molecular modelling studies of novel indolin-2-ones designing as FGFR inhibitors

• Những tác giả chính: Güneş Çoban (Tác giả), Fadime Aydın Köse (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2019-11-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

A series of novel 3,5-disubstituted indolin-2-ones were designed and synthesized as selective FGFR inhibitors. In the design process of 3,5-disubstituted indolin-2-ones for FGFRs, molecular docking studies were performed to generate and optimize novel compounds which have FGFR inhibitory potency, th...