Effect of interleukin-1 antagonist on growth of children with colchicine resistant or intolerant FMF

• Main Authors: Shiran Pinchevski-Kadir (Author), Maya Gerstein (Author), Oren Pleniceanu (Author), Yonatan Yacobi (Author), Asaf Vivante (Author), Ortal Erez Granat (Author), Shiri Spielman (Author), Rotem Semo Oz (Author), Irit Tirosh (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Familial Mediterranean Fever (FMF) is the most common monogentic autoinflammatory disease. FMF results from mutations in MEFV, which lead to a pro-inflammatory state and increased production of Interleukin 1 beta subunit (IL-1b) by myeloid cells. Despite the overall positive re...