Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways

• Main Authors: Xiu-lian Lin (Author), Ya-ning Shi (Author), Yu-ling Cao (Author), Xi Tan (Author), Ya-ling Zeng (Author), Shi-teng Luo (Author), Ya-mei Li (Author), Li Qin (Author), Bo-hou Xia (Author), Rong-geng Fu (Author), Li-mei Lin (Author), Kai Li (Author), Deliang Cao (Author), Jian-guo Zeng (Author), Duan-fang Liao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent years, small intestine as a key target in the treatment of Inflammatory bowel disease caused by NSAIDs has become a hot topic. Sanguinarine (SA) is one of the main alkaloids in the Macleaya cordata extracts with strong pharmacological activity of anti-tumor, anti-inflammation and anti-oxid...