Role of Hydrogen Peroxide in Cyclosporine-Induced Renal Tubular Cell (LLC-PK1) Injury

We examined the role of hydrogen peroxide production in cyclosporine A (CsA)-induced LLC-PK1 injury. After exposure to CsA (0.1 μM - 100 μM), cytotoxicity assessed by lactate dehydrogenase release to the media increased dose-dependently. LLC-PK1 cells produced hydrogen peroxide, visualized by 2,7-di...

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Main Authors: Masashi Nishida (Author), Hiroshi Ogawa (Author), Megumi Tamai (Author), Kohhei Ishiwari (Author), Kenji Hamaoka (Author)
Format: Book
Published: Elsevier, 2003-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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