Inhibition of Histone Methyltransferase, Histone Deacetylase, and β-Catenin Synergistically Enhance the Cardiac Potential of Bone Marrow Cells

• 主要な著者: Jinpu Yang (著者), Keerat Kaur (著者), John G. Edwards (著者), Carol A. Eisenberg (著者), Leonard M. Eisenberg (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2017-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Previously, we reported that treatment with the G9a histone methyltransferase inhibitor BIX01294 causes bone marrow mesenchymal stem cells (MSCs) to exhibit a cardiocompetent phenotype, as indicated by the induction of the precardiac markers Mesp1 and brachyury. Here, we report that combining the hi...