Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs in HMMR as Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients

• Main Authors: Behzad Bidadi (Author), Duan Liu (Author), Krishna R. Kalari (Author), Matthias Rubner (Author), Alexander Hein (Author), Matthias W. Beckmann (Author), Brigitte Rack (Author), Wolfgang Janni (Author), Peter A. Fasching (Author), Richard M. Weinshilboum (Author), Liewei Wang (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Neutropenia secondary to chemotherapy in breast cancer patients can be life-threatening and there are no biomarkers available to predict the risk of drug-induced neutropenia in those patients. We previously performed a genome-wide association study (GWAS) for neutropenia events in women with breast...