Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
Objective: The mitochondrial pyruvate carrier (MPC) has emerged as a promising drug target for metabolic disorders, including non-alcoholic steatohepatitis and diabetes, metabolically dependent cancers and neurodegenerative diseases. A range of structurally diverse small molecule inhibitors have bee...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2022-06-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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