Molecular analysis of the <it>APC </it>and <it>MUTYH </it>genes in Galician and Catalonian FAP families: a different spectrum of mutations?

• Main Authors: Gómez-Fernández Nuria (Author), Castellví-Bel Sergi (Author), Fernández-Rozadilla Ceres (Author), Balaguer Francesc (Author), Muñoz Jenifer (Author), Madrigal Irene (Author), Milà Montserrat (Author), Graña Begoña (Author), Vega Ana (Author), Castells Antoni (Author), Carracedo Ángel (Author), Ruiz-Ponte Clara (Author)
• Formato: Libro
• Publicado: BMC, 2009-06-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Familial adenomatous polyposis (FAP) is an autosomal dominant-inherited colorectal cancer syndrome, caused by germline mutations in the <it>APC </it>gene. Recently, biallelic mutations in <it>MUTYH </it>have a...