Critical roles of super-enhancers in the pathogenesis of autoimmune diseases

• Main Authors: Kaoru Yamagata (Author), Shingo Nakayamada (Author), Yoshiya Tanaka (Author)
• 格式: 图书
• 出版: BMC, 2020-08-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract The super-enhancer (SE) is a cluster of enhancers involved in cell differentiation via enhanced gene expression that determines cell identity. Meanwhile, genome-wide association studies (GWASs) have reported the presence of gene clusters containing single nucleotide polymorphisms (SNPs) sus...