Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles

• Main Authors: Jian Hou (Author), E. Sun (Author), Zhen-Hai Zhang (Author), Jing Wang (Author), Lei Yang (Author), Li Cui (Author), Zhong-Cheng Ke (Author), Xiao-Bin Tan (Author), Xiao-Bin Jia (Author), Huixia Lv (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to establish a paclitaxel (PTX)-loaded mixed micelle delivery system (PTX-TP-M) with vitamin E-TPGS (TPGS) and Plasdone®S-630 Copovidone (PVPS630) as carriers to improve the solubility, oral absorption, and anti-tumor activity of PTX against lung cancer. In this study, PTX-...