Expanded CD133+ Cells from Human Umbilical Cord Blood Improved Heart Function in Rats after Severe Myocardial Infarction

• Main Authors: Alejandro Correa (Author), Gabriel Salles Ottoboni (Author), Alexandra Cristina Senegaglia (Author), Luiz Guilherme Achcar Capriglione (Author), Nelson Itiro Miyague (Author), Lidiane Maria Boldrini Leite (Author), Valderez Ravaglio Jamur (Author), Carmen Lúcia Kuniyoshi Rebelatto (Author), Márcia Olandoski (Author), Paulo Roberto Slud Brofman (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacological approaches are partially effective in limiting infarct size. Cell therapies using a cell population enriched with endothelial progenitor cells (EPCs) CD133+ have opened new perspectives for the treatment of ischemic areas after infarction. This preclinical study evaluated the effect...