Ivermectin and its synthetic derivatives - A new class of anticancer agents

• Main Authors: Michał Sulik (Author), Dagmara Otto-Ślusarczyk (Author), Michał Antoszczak (Author), Marta Struga (Author), Adam Huczyński (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ivermectin (IVR) is a 16-membered macrocyclic lactone of Nobel prize-honored distinction, showing a broad spectrum of biological activity, especially antiparasitic. We have recently designed a practical and scalable procedure for the synthesis of IVR derivatives with a rearranged oxahydrindene (hexa...