Brief isoflurane administration as an adjunct treatment to control organophosphate-induced convulsions and neuropathology

• Main Authors: Narayanan Puthillathu (Author), John R. Moffett (Author), Alexandru Korotcov (Author), Asamoah Bosomtwi (Author), Ranjini Vengilote (Author), Jishnu K. S. Krishnan (Author), Erik A. Johnson (Author), Peethambaran Arun (Author), Aryan M. Namboodiri (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Organophosphate-based chemical agents (OP), including nerve agents and certain pesticides such as paraoxon, are potent acetylcholinesterase inhibitors that cause severe convulsions and seizures, leading to permanent central nervous system (CNS) damage if not treated promptly. The current treatment r...