Human Albumin Fragments Nanoparticles as PTX Carrier for Improved Anti-cancer Efficacy

• Main Authors: Liang Ge (Author), Xinru You (Author), Jun Huang (Author), Yuejian Chen (Author), Li Chen (Author), Ying Zhu (Author), Yuan Zhang (Author), Xiqiang Liu (Author), Jun Wu (Author), Qian Hai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

For enhanced anti-cancer performance, human serum albumin fragments (HSAFs) nanoparticles (NPs) were developed as paclitaxel (PTX) carrier in this paper. Human albumins were broken into fragments via degradation and crosslinked by genipin to form HSAF NPs for better biocompatibility, improved PTX dr...