SARS-CoV-2 spike protein accelerates systemic sclerosis by increasing inflammatory cytokines, Th17 cells, and fibrosis

• Main Authors: Ha Yeon Jeong (Author), Jin-Sil Park (Author), Jin Seok Woo (Author), Kun Hee Lee (Author), Jeong Won Choi (Author), Hye Yeon Kang (Author), Hyun Sik Na (Author), Yeon Su Lee (Author), In Gyu Um (Author), Sung-Hwan Park (Author), Mi-La Cho (Author)
• Format: Book
• Published: BMC, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Coronavirus disease 2019 (COVID-19) induces a dysfunctional immune response, inflammation, autoantibody production, and coagulopathy, which are symptoms that bear resemblance to those of autoimmune diseases, including systemic sclerosis (SSc). Methods While there is a single case...