Identification of key genes in calcific aortic valve disease via weighted gene co-expression network analysis

• Main Authors: Jin-Yu Sun (Author), Yang Hua (Author), Hui Shen (Author), Qiang Qu (Author), Jun-Yan Kan (Author), Xiang-Qing Kong (Author), Wei Sun (Author), Yue-Yun Shen (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Calcific aortic valve disease (CAVD) is the most common subclass of valve heart disease in the elderly population and a primary cause of aortic valve stenosis. However, the underlying mechanisms remain unclear. Methods The gene expression profiles of GSE83453, GSE51472, and GSE12...