Identification of key genes in calcific aortic valve disease via weighted gene co-expression network analysis

• Autores principales: Jin-Yu Sun (Autor), Yang Hua (Autor), Hui Shen (Autor), Qiang Qu (Autor), Jun-Yan Kan (Autor), Xiang-Qing Kong (Autor), Wei Sun (Autor), Yue-Yun Shen (Autor)
• Formato: Libro
• Publicado: BMC, 2021-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Calcific aortic valve disease (CAVD) is the most common subclass of valve heart disease in the elderly population and a primary cause of aortic valve stenosis. However, the underlying mechanisms remain unclear. Methods The gene expression profiles of GSE83453, GSE51472, and GSE12...