MMHD [(S,E)-2-Methyl-1-(2-methylthiazol-4-yl) hexa-1,5-dien-ol], a Novel Synthetic Compound Derived From Epothilone, Suppresses Nuclear Factor-κB-Mediated Cytokine Expression in Lipopolysaccharide-Stimulated BV-2 Microglia

• Main Authors: Na-Ra Jeon (Author), Sushruta Koppula (Author), Byung-Wook Kim (Author), Su-Ho Park (Author), Hyo-Won Lee (Author), Dong-Kug Choi (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effects of MMHD [(S,E)-2-methyl-1-(2-methylthiazol-4-yl) hexa-1,5-dien-ol], a novel synthetic compound derived from epothilone, was investigated for its effects on the expression of proinflammatory mediators in lipopolysaccharide-stimulated BV-2 microglia. MMHD attenuated the expressions of indu...