A phase I study to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic profiles of ocular GLH8NDE in healthy male adults

• Hlavní autoři: Jihyun Jung (Autor), Ki Young Huh (Autor), Xuanyou Jin (Autor), Ahnul Ha (Autor), Ki Ho Park (Autor), Jun Sang Park (Autor), Eunjung Kim (Autor), Jaehwi Lee (Autor), In‐Jin Jang (Autor), Howard Lee (Autor)
• Médium: Kniha
• Vydáno: Wiley, 2022-02-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract GLH8NDE, a derivative of eupatilin, is currently under development to treat dry eye disease. We conducted a randomized, double‐masked, placebo‐controlled, single‐ and multiple‐day study to evaluate safety, tolerability, pharmacodynamics, and pharmacokinetics of ocular GLH8NDE in healthy mal...