Cleomin Exerts Acute Antinociceptive Effects in Mice via GABA_B and Muscarinic Receptors

• Main Authors: Luíza Carolina França Opretzka (Author), Max Denisson Maurício Viana (Author), Alyne Almeida de Lima (Author), Thalisson Amorim de Souza (Author), Marcus Tullius Scotti (Author), Josean Fechine Tavares (Author), Marcelo Sobral da Silva (Author), Milena Botelho Pereira Soares (Author), Cristiane Flora Villarreal (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cleomin, a 1,3-oxazolidine-2-thione, was recently isolated from <i>Neocalyptrocalyx longifolium</i>, a species traditionally used for treating painful conditions. Reports about the pharmacological activities of cleomin are lacking. Here, the antinociceptive effects of cleomin were invest...