New view on alcoholic liver disease - potential role of PD1/PDL-1 pathway in the disease pathogenesis

• मुख्य लेखकों: Katarzyna Adamczyk (लेखक), Beata Kasztelan-Szczerbińska (लेखक), Anna Rycyk (लेखक), Halina Cichoż-Lach (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Kazimierz Wielki University, 2019-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Exposure to chronic, excessive alcohol consumption, its breakdown metabolites, and gut-derived endotoxins dysregulate immune signaling leading to activation of inflammation. As a result, the non-resolving inflammatory response and development of alcoholic liver disease (ALD) may occur....