Analysis of REST binding sites with canonical and non-canonical motifs in human cell lines

Abstract Background Repressor element 1 (RE1) silencing transcription factor (REST) is a transcriptional repressor abundantly expressed in aging human brains. It is known to regulate genes associated with oxidative stress, inflammation, and neurological disorders by binding to a canonical form of se...

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Main Authors: Jaejoon Choi (Author), Eunjung Alice Lee (Author)
Format: Bog
Udgivet: BMC, 2024-04-01T00:00:00Z.
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