Structural and functional analysis of a platelet-activating lysophosphatidylcholine of Trypanosoma cruzi.

• Autori principali: Felipe Gazos-Lopes (Autore), Mauricio M Oliveira (Autore), Lucas V B Hoelz (Autore), Danielle P Vieira (Autore), Alexandre F Marques (Autore), Ernesto S Nakayasu (Autore), Marta T Gomes (Autore), Nasim G Salloum (Autore), Pedro G Pascutti (Autore), Thaïs Souto-Padrón (Autore), Robson Q Monteiro (Autore), Angela H Lopes (Autore), Igor C Almeida (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Trypanosoma cruzi is the causative agent of the life-threatening Chagas disease, in which increased platelet aggregation related to myocarditis is observed. Platelet-activating factor (PAF) is a potent intercellular lipid mediator and second messenger that exerts its activity through a PAF-specific...