Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice

SUMMARY Abnormal Notch signaling in humans results in Alagille syndrome, a pleiotropic disease characterized by a paucity of intrahepatic bile ducts (IHBDs). It is not clear how IHBD paucity develops as a consequence of atypical Notch signaling, whether by a developmental lack of bile duct formation...

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Main Authors: Erin E. Sparks (Author), Daniel S. Perrien (Author), Kari A. Huppert (Author), Todd E. Peterson (Author), Stacey S. Huppert (Author)
Format: Book
Published: The Company of Biologists, 2011-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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