Modulation of the kappa and mu opioid axis for the treatment of chronic pruritus: A review of basic science and clinical implicationsCapsule Summary

• Главные авторы: Sarina Elmariah, MD, PhD (Автор), Sarah Chisolm, MD (Автор), Thomas Sciascia, MD (Автор), Shawn G. Kwatra, MD (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2022-06-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Introduction: Treating chronic pruritus is challenging for dermatologists due to the lack of therapeutic options. We review the effects of κ-opioid receptor (KOR) and μ-opioid receptor (MOR) in the modulation of itch, summarize evidence supporting the efficacy and safety of opioid receptor-targeting...