Effect of platelet-activating factor on the growth of human erythroid and myeloid CD34+ progenitors

• Main Authors: F. Dupuis (Author), N. Gachard (Author), A. Allegraud (Author), C. Dulery (Author), V. Praloran (Author), Y. Denizot (Author)
• Format: Book
• Published: Hindawi Limited, 1998-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have assessed the effect of platelet-activating factor (PAF), a biologically active phospholipid present in the human marrow, on the growth of human marrow and blood CD34+ progenitors. While the metabolization rate of PAF by CD34+ cells is low (weak acetylhydrolase and acylation processes) it is...