Sedative and Immunosuppressive Effects of Dexmedetomidine in Transplantation

• Main Authors: Chen-Fang Lee (Author), Chih-Hsien Cheng (Author), Hao-Chien Hung (Author), Jin-Chiao Lee (Author), Yu-Chiao Wang (Author), Tsung-Han Wu (Author), Ting-Jung Wu (Author), Hong-Shiue Chou (Author), Kun-Ming Chan (Author), Wei-Chen Lee (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dexmedetomidine, an α2-adrenergic receptor agonist, is used as an anti-anxiety medication. It exerts a cholinergic effect, thereby reducing the release of tumor necrosis factor alpha (TNF-α). We hypothesized that the use of dexmedetomidine as a sedative agent in transplantation would also protect al...