Rational drug design, synthesis, and biological evaluation of novel N-(2-arylaminophenyl)-2,3-diphenylquinoxaline-6-sulfonamides as potential antimalarial, antifungal, and antibacterial agents

• Main Authors: Ahmed Hassen Shntaif (Author), Sharuk Khan (Author), Ganesh Tapadiya (Author), Anand Chettupalli (Author), Shweta Saboo (Author), Mohd Sayeed Shaikh (Author), Falak Siddiqui (Author), Ramkoteswra Rao Amara (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Sulfanilamide, sulfadiazine, and dapsone were the first sulfonamides to be used to treat malaria by disrupting the folate biosynthesis process, which is essential for parasite survival. Therefore, we aimed to synthesize novel N-(2-arylaminophenyl)-2,3-diphenylquinoxaline-6-sulfonamide der...