Wee1 Inhibitor AZD1775 Effectively Inhibits the Malignant Phenotypes of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo

• Päätekijät: Shuning Bi (Tekijä), Qiuren Wei (Tekijä), Zhijun Zhao (Tekijä), Liang Chen (Tekijä), Chaojie Wang (Tekijä), Songqiang Xie (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Esophageal squamous cell carcinoma (ESCC) is a common malignant diagnosed cancer with increasing incidence rate and few treatment options. As a specific small-molecule inhibitor of the Wee1 tyrosine kinase, AZD1775 has previously shown potent antitumor effect on multiple types of cancer in various p...