Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice

• Main Authors: Kadriye DEMİRKAYA (Author), Özlem Martı AKGÜN (Author), Buğra ŞENEL (Author), Zeynep ÖNCEL TORUN (Author), Melik SEYREK (Author), Enza LACİVİTA (Author), Marcello LEOPOLDO (Author), Ahmet DOĞRUL (Author)
• Format: Book
• Published: University of São Paulo.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT The most recently identified serotonin (5-HT) receptor is the 5-HT7 receptor. The antinociceptive effects of a 5-HT7 receptor agonist have been shown in neuropathic and inflammatory animal models of pain. A recent study demonstrated the functional expression of 5-HT7 receptors in the substa...