The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character

The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character

Particle size reduction is a commonly used process to improve the solubility and the dissolution of drug formulations. The solubility of a drug in the gastrointestinal tract is a crucial parameter, because it can greatly influence the bioavailability. This work provides a comprehensive investigation...

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Main Authors: Dóra Csicsák (Author), Rita Szolláth (Author), Szabina Kádár (Author), Rita Ambrus (Author), Csilla Bartos (Author), Emese Balogh (Author), István Antal (Author), István Köteles (Author), Petra Tőzsér (Author), Vivien Bárdos (Author), Péter Horváth (Author), Enikő Borbás (Author), Krisztina Takács-Novák (Author), Bálint Sinkó (Author), Gergely Völgyi (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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