Multivariate optimization and evaluation of quaternary mixture in bulk and co-formulated dosage forms by central composite design

• Main Authors: Rama Tulasi Jampana (Author), Prameela Rani Avula (Author), Panikumar Durga Anumolu (Author)
• Formato: Libro
• Publicado: SpringerOpen, 2021-05-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract Background The current study describes the use of central composite design for multivariate optimization of resolution and retention time, taking into account different critical method parameters like organic phase, pH, flow rate, and wavelength for risk assessment. The chromatographic meth...