RhoA/ROCK2 signalling is enhanced by PDGF‐AA in fibro‐adipogenic progenitor cells: implications for Duchenne muscular dystrophy

• मुख्य लेखकों: Esther Fernández‐Simón (लेखक), Xavier Suárez‐Calvet (लेखक), Ana Carrasco‐Rozas (लेखक), Patricia Piñol‐Jurado (लेखक), Susana López‐Fernández (लेखक), Gemma Pons (लेखक), Joan Josep Bech Serra (लेखक), Carolina de laTorre (लेखक), Noemí deLuna (लेखक), Eduard Gallardo (लेखक), Jordi Díaz‐Manera (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background The lack of dystrophin expression in Duchenne muscular dystrophy (DMD) induces muscle fibre and replacement by fibro‐adipose tissue. Although the role of some growth factors in the process of fibrogenesis has been studied, pathways activated by PDGF‐AA have not been described so...