Genotype-phenotype correlation analysis of MYO15A variants in autosomal recessive non-syndromic hearing loss

• Main Authors: Jing Zhang (Author), Jing Guan (Author), Hongyang Wang (Author), Linwei Yin (Author), Dayong Wang (Author), Lidong Zhao (Author), Huifang Zhou (Author), Qiuju Wang (Author)
• Format: Book
• Published: BMC, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background MYO15A variants are responsible for human non-syndromic autosomal recessive deafness (DFNB3). The majority of MYO15A variants are associated with a congenital severe-to-profound hearing loss phenotype, except for MYO15A variants in exon 2, which cause a milder auditory phenotype,...