UPLC-MS/MS method for Icariin and metabolites in whole blood of C57 mice: development, validation, and pharmacokinetics study

Icariin, a Chinese medicinal herb with significant effects on Alzheimer's disease, lacks pharmacokinetic data in mice. To address this, a UPLC-MS/MS method was developed and validated for quantifying Icariin and its metabolites, Icariside I and Icariside II, in the whole blood of mice. The meth...

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Main Authors: Wei Liu (Author), Xiuyun Li (Author), Na Li (Author), Ze Mi (Author), Jinjing Che (Author)
Format: Book
Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
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