Dimerization and lysine substitution of melittin have differing effects on bacteria
IntroductionMelittin is a potent antimicrobial peptide from bee venom that is effective against both Gram-positive and Gram-negative bacteria. However, it is extremely toxic to mammalian cells and, as yet, has no clinical use. Modifications to its amino acid sequence, cyclization, truncation, and di...
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Frontiers Media S.A.,
2024-10-01T00:00:00Z.
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