p53: A double-edged sword in tumor ferroptosis

• Main Authors: Haixia Ji (Author), Wenzhe Wang (Author), Xia Li (Author), Xiaoying Han (Author), Xinyu Zhang (Author), Juan Wang (Author), Changxiao Liu (Author), Luqi Huang (Author), Wenyuan Gao (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is a type of lipid peroxidation-induced cell death that can be regulated in various ways, from changing the activity of antioxidant enzymes to the levels of transcription factors. The p53 tumor suppressor gene is the ''guardian of the genome'' and is involved in contr...