Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3β-OH

Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3β-OH

We recently reported that a neurosteroid analogue with T-channel-blocking properties (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile (3β-OH), induced hypnosis in rat pups without triggering neuronal apoptosis. Furthermore, we found that the inhibition of the CaV3.1 isoform of T-channels contributes...

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Main Authors: Tamara Timic Stamenic (Author), Francesca M. Manzella (Author), Stefan Maksimovic (Author), Kathiresan Krishnan (Author), Douglas F. Covey (Author), Vesna Jevtovic-Todorovic (Author), Slobodan M. Todorovic (Author)
Format: Book
Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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