Comparative AAV-eGFP Transgene Expression Using Vector Serotypes 1-9, 7m8, and 8b in Human Pluripotent Stem Cells, RPEs, and Human and Rat Cortical Neurons

Recombinant adeno-associated virus (rAAV), produced from a nonpathogenic parvovirus, has become an increasing popular vector for gene therapy applications in human clinical trials. However, transduction and transgene expression of rAAVs can differ across in vitro and ex vivo cellular transduction st...

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Autors principals: Thu T. Duong (Autor), James Lim (Autor), Vidyullatha Vasireddy (Autor), Tyler Papp (Autor), Hung Nguyen (Autor), Lanfranco Leo (Autor), Jieyan Pan (Autor), Shangzhen Zhou (Autor), H. Isaac Chen (Autor), Jean Bennett (Autor), Jason A. Mills (Autor)
Format: Llibre
Publicat: Hindawi Limited, 2019-01-01T00:00:00Z.
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