Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease

• Main Authors: Frederikke E. Sembach (Author), Helene M. Ægidius (Author), Lisbeth N. Fink (Author), Thomas Secher (Author), Annemarie Aarup (Author), Jacob Jelsing (Author), Niels Vrang (Author), Bo Feldt-Rasmussen (Author), Kristoffer T. G. Rigbolt (Author), Jens C. Nielsen (Author), Mette V. Østergaard (Author)
• Format: Book
• Published: The Company of Biologists, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The current understanding of molecular mechanisms driving diabetic kidney disease (DKD) is limited, partly due to the complex structure of the kidney. To identify genes and signalling pathways involved in the progression of DKD, we compared kidney cortical versus glomerular transcriptome profiles in...