Biochanin A abrogates osteoclastogenesis in type 2 diabetic osteoporosis via regulating ROS/MAPK signaling pathway based on integrating molecular docking and experimental validation

• Main Authors: Qi He (Author), Junzheng Yang (Author), Weijian Chen (Author), Zhaofeng Pan (Author), Baihao Chen (Author), Jiaxu Zeng (Author), Nenling Zhang (Author), Yuewei Lin (Author), Chuyi Chen (Author), Jiacong Xiao (Author), Miao Li (Author), Shaocong Li (Author), Haibin Wang (Author), Peng Chen (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background There are accumulating type 2 diabetes patients who have osteoporosis simultaneously. More effective therapeutic strategies should be discovered. Biochanin A (BCA) has been indicated that can play a role in improving metabolic disorders of type 2 diabetes and preventing osteoporo...