Quercetin Attenuates d-GaLN-Induced L02 Cell Damage by Suppressing Oxidative Stress and Mitochondrial Apoptosis via Inhibition of HMGB1

• Main Authors: Peng Fang (Author), Jiajun Liang (Author), Xuejiao Jiang (Author), Xian Fang (Author), Mengli Wu (Author), Xiaoyi Wei (Author), Wenlong Yang (Author), Weixin Hou (Author), Qiuyun Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High mobility group box-1 (HMGB1) plays an important role in various liver injuries. In the case of acute liver injury, it leads to aseptic inflammation and other reactions, and also regulates specific cell death responses in chronic liver injury. HMGB1 has been demonstrated to be a good therapeutic...