A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease

• Main Authors: Ida Unhammer Njerve (Author), Sissel Åkra (Author), Thomas W. Weiss (Author), Svein Solheim (Author), Reidun Øvstebø (Author), Hans Christian D. Aass (Author), Rune Byrkjeland (Author), Harald Arnesen (Author), Ingebjørg Seljeflot (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Promising results regarding potential anti-inflammatory and antiatherosclerotic effects of gliptins have been reported. Our aim was to investigate whether saxagliptin treatment modifies expression of inflammatory markers, primarily in peripheral blood mononuclear cells (PBMCs) and in cir...