Lentiviral vectors transduce lung stem cells without disrupting plasticity
Life-long expression of a gene therapy agent likely requires targeting stem cells. Here we ask the question: does viral vector transduction or ectopic expression of a therapeutic transgene preclude airway stem cell function? We used a lentiviral vector containing a GFP or cystic fibrosis transmembra...
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Format: | Book |
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Elsevier,
2021-09-01T00:00:00Z.
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Internet
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A1234.567 |
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Copy 1 | Available |