How translational modeling in oncology needs to get the mechanism just right

• Päätekijät: James W. T. Yates (Tekijä), David A Fairman (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2022-03-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Translational model‐based approaches have played a role in increasing success in the development of novel anticancer treatments. However, despite this, significant translational uncertainty remains from animal models to patients. Optimization of dose and scheduling (regimen) of drugs to max...