The role of botanical triterpenoids and steroids in bile acid metabolism, transport, and signaling: Pharmacological and toxicological implications

• Main Authors: Zichen Luo (Author), Wei Zhou (Author), Tong Xie (Author), Weichen Xu (Author), Chen Shi (Author), Zihan Xiao (Author), Yu Si (Author), Yan Ma (Author), Qingling Ren (Author), Liuqing Di (Author), Jinjun Shan (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bile acids (BAs) are synthesized by the host liver from cholesterol and are delivered to the intestine, where they undergo further metabolism by gut microbes and circulate between the liver and intestines through various transporters. They serve to emulsify dietary lipids and act as signaling molecu...