SIRT3 Modulates Endothelial Mitochondrial Redox State during Insulin Resistance

• मुख्य लेखकों: Elisa Martino (लेखक), Anna Balestrieri (लेखक), Camilla Anastasio (लेखक), Martina Maione (लेखक), Luigi Mele (लेखक), Domenico Cautela (लेखक), Giuseppe Campanile (लेखक), Maria Luisa Balestrieri (लेखक), Nunzia D'Onofrio (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Emerging evidence indicates that defects in sirtuin signaling contribute to impaired glucose and lipid metabolism, resulting in insulin resistance (IR) and endothelial dysfunction. Here, we examined the effects of palmitic acid (PA) treatment on mitochondrial sirtuins (SIRT2, SIRT3, SIRT4, and SIRT5...