SIRT3 Modulates Endothelial Mitochondrial Redox State during Insulin Resistance

• Main Authors: Elisa Martino (Author), Anna Balestrieri (Author), Camilla Anastasio (Author), Martina Maione (Author), Luigi Mele (Author), Domenico Cautela (Author), Giuseppe Campanile (Author), Maria Luisa Balestrieri (Author), Nunzia D'Onofrio (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Emerging evidence indicates that defects in sirtuin signaling contribute to impaired glucose and lipid metabolism, resulting in insulin resistance (IR) and endothelial dysfunction. Here, we examined the effects of palmitic acid (PA) treatment on mitochondrial sirtuins (SIRT2, SIRT3, SIRT4, and SIRT5...