Sonic hedgehog signaling in the development of the mouse hypothalamus

• Main Authors: Sandra eBlaess (Author), Nora eSzabo (Author), Roberta eHaddad-Tóvolli (Author), Xunlei eZhou (Author), Gonzalo eAlvarez-Bolado (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The expression pattern of Sonic Hedgehog (Shh) in the developing hypothalamus changes over time. Shh is initially expressed in the prechordal mesoderm and later in the hypothalamic neuroepithelium-- first medially, and then in two off-medial domains. This dynamic expression suggests that Shh might r...