PEG-lipid-PLGA hybrid nanoparticles loaded with berberine-phospholipid complex to facilitate the oral delivery efficiency

• Main Authors: Fei Yu (Author), Mingtao Ao (Author), Xiao Zheng (Author), Nini Li (Author), Junjie Xia (Author), Yang Li (Author), Donghui Li (Author), Zhenqing Hou (Author), Zhongquan Qi (Author), Xiao Dong Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The natural product berberine (BBR), present in various plants, arouses great interests because of its numerous pharmacological effects. However, the further development and application of BBR had been hampered by its poor oral bioavailability. In this work, we report on polymer-lipid hybrid nanopar...