KV11.1 Potassium Channel and the Na+/H+ Antiporter NHE1 Modulate Adhesion-Dependent Intracellular pH in Colorectal Cancer Cells

• मुख्य लेखकों: Jessica Iorio (लेखक), Claudia Duranti (लेखक), Tiziano Lottini (लेखक), Elena Lastraioli (लेखक), Giacomo Bagni (लेखक), Andrea Becchetti (लेखक), Annarosa Arcangeli (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Increasing evidence indicates that ion channels and transporters cooperate in regulating different aspects of tumor pathophysiology. In cancer cells, H+/HCO3- transporters usually invert the transmembrane pH gradient typically observed in non-neoplastic cells, which is thought to contribute to cance...