Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells

Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells

Introduction: Sarcopenia is defined as a loss of muscle mass and strength. ATP homeostasis is crucial during myogenesis. We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and tenofovir (inhibits ATP release) in a myoblast cell li...

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Main Authors: Miguel Marco-Bonilla (Author), Raquel Herencia (Author), María Fresnadillo (Author), Fernando Huete-Toral (Author), Gonzalo Carracedo (Author), Raquel Largo (Author), Gabriel Herrero-Beaumont (Author), Aránzazu Mediero (Author)
Format: Book
Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
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